Parkinson's Disease (PD) is a progressive nervous system disorder that has affected more than 5.8 million people, especially the elderly. Due to the complexity of its symptoms and its similarity to other neurological disorders, early detection requires neurologists or PD specialists to be involved, which is not accessible to most old people. Therefore, we integrate smart mobile devices with AI technologies. In this paper, we introduce the framework of our developed PD early detection system which combines different tasks evaluating both motor and non-motor symptoms. With the developed model, we help users detect PD punctually in non-clinical settings and figure out their most severe symptoms. The results are expected to be further used for PD rehabilitation guidance and detection of other neurological disorders.

Gigapixel Medical图像提供了大量的数据，包括形态学纹理和空间信息。由于组织学的数据量表较大，​​深度学习方法作为特征提取器起着越来越重要的作用。现有的解决方案在很大程度上依赖卷积神经网络（CNN）进行全局像素级分析，从而使潜在的局部几何结构（例如肿瘤微环境中的细胞之间的相互作用均未探索。事实证明，医学图像中的拓扑结构与肿瘤进化密切相关，可以很好地表征图。为了获得下游肿瘤学任务的更全面的表示，我们提出了一个融合框架，以增强CNN捕获的全局图像级表示，并使用图形神经网络（GNN）学习的细胞级空间信息的几何形状。融合层优化了全局图像和单元图的协作特征之间的集成。已经开发了两种融合策略：一种具有MLP的融合策略，这很简单，但通过微调而有效，而Transformer获得了融合多个网络的冠军。我们评估了从大型患者群体和胃癌策划的组织学数据集中的融合策略，以完成三个生物标志物预测任务。两种型号的表现都优于普通CNN或GNN，在各种网络骨架上达到了超过5％的AUC提高。实验结果在医学图像分析中将图像水平的形态特征与细胞空间关系相结合的必要性。代码可在https://github.com/yiqings/hegnnenhancecnn上找到。

A recent study has shown a phenomenon called neural collapse in that the within-class means of features and the classifier weight vectors converge to the vertices of a simplex equiangular tight frame at the terminal phase of training for classification. In this paper, we explore the corresponding structures of the last-layer feature centers and classifiers in semantic segmentation. Based on our empirical and theoretical analysis, we point out that semantic segmentation naturally brings contextual correlation and imbalanced distribution among classes, which breaks the equiangular and maximally separated structure of neural collapse for both feature centers and classifiers. However, such a symmetric structure is beneficial to discrimination for the minor classes. To preserve these advantages, we introduce a regularizer on feature centers to encourage the network to learn features closer to the appealing structure in imbalanced semantic segmentation. Experimental results show that our method can bring significant improvements on both 2D and 3D semantic segmentation benchmarks. Moreover, our method ranks 1st and sets a new record (+6.8% mIoU) on the ScanNet200 test leaderboard. Code will be available at https://github.com/dvlab-research/Imbalanced-Learning.

Weakly-supervised object localization aims to indicate the category as well as the scope of an object in an image given only the image-level labels. Most of the existing works are based on Class Activation Mapping (CAM) and endeavor to enlarge the discriminative area inside the activation map to perceive the whole object, yet ignore the co-occurrence confounder of the object and context (e.g., fish and water), which makes the model inspection hard to distinguish object boundaries. Besides, the use of CAM also brings a dilemma problem that the classification and localization always suffer from a performance gap and can not reach their highest accuracy simultaneously. In this paper, we propose a casual knowledge distillation method, dubbed KD-CI-CAM, to address these two under-explored issues in one go. More specifically, we tackle the co-occurrence context confounder problem via causal intervention (CI), which explores the causalities among image features, contexts, and categories to eliminate the biased object-context entanglement in the class activation maps. Based on the de-biased object feature, we additionally propose a multi-teacher causal distillation framework to balance the absorption of classification knowledge and localization knowledge during model training. Extensive experiments on several benchmarks demonstrate the effectiveness of KD-CI-CAM in learning clear object boundaries from confounding contexts and addressing the dilemma problem between classification and localization performance.

Witnessing the impressive achievements of pre-training techniques on large-scale data in the field of computer vision and natural language processing, we wonder whether this idea could be adapted in a grab-and-go spirit, and mitigate the sample inefficiency problem for visuomotor driving. Given the highly dynamic and variant nature of the input, the visuomotor driving task inherently lacks view and translation invariance, and the visual input contains massive irrelevant information for decision making, resulting in predominant pre-training approaches from general vision less suitable for the autonomous driving task. To this end, we propose PPGeo (Policy Pre-training via Geometric modeling), an intuitive and straightforward fully self-supervised framework curated for the policy pretraining in visuomotor driving. We aim at learning policy representations as a powerful abstraction by modeling 3D geometric scenes on large-scale unlabeled and uncalibrated YouTube driving videos. The proposed PPGeo is performed in two stages to support effective self-supervised training. In the first stage, the geometric modeling framework generates pose and depth predictions simultaneously, with two consecutive frames as input. In the second stage, the visual encoder learns driving policy representation by predicting the future ego-motion and optimizing with the photometric error based on current visual observation only. As such, the pre-trained visual encoder is equipped with rich driving policy related representations and thereby competent for multiple visuomotor driving tasks. Extensive experiments covering a wide span of challenging scenarios have demonstrated the superiority of our proposed approach, where improvements range from 2% to even over 100% with very limited data. Code and models will be available at https://github.com/OpenDriveLab/PPGeo.

In this work, we focus on instance-level open vocabulary segmentation, intending to expand a segmenter for instance-wise novel categories without mask annotations. We investigate a simple yet effective framework with the help of image captions, focusing on exploiting thousands of object nouns in captions to discover instances of novel classes. Rather than adopting pretrained caption models or using massive caption datasets with complex pipelines, we propose an end-to-end solution from two aspects: caption grounding and caption generation. In particular, we devise a joint Caption Grounding and Generation (CGG) framework based on a Mask Transformer baseline. The framework has a novel grounding loss that performs explicit and implicit multi-modal feature alignments. We further design a lightweight caption generation head to allow for additional caption supervision. We find that grounding and generation complement each other, significantly enhancing the segmentation performance for novel categories. We conduct extensive experiments on the COCO dataset with two settings: Open Vocabulary Instance Segmentation (OVIS) and Open Set Panoptic Segmentation (OSPS). The results demonstrate the superiority of our CGG framework over previous OVIS methods, achieving a large improvement of 6.8% mAP on novel classes without extra caption data. Our method also achieves over 15% PQ improvements for novel classes on the OSPS benchmark under various settings.

Nearest-Neighbor (NN) classification has been proven as a simple and effective approach for few-shot learning. The query data can be classified efficiently by finding the nearest support class based on features extracted by pretrained deep models. However, NN-based methods are sensitive to the data distribution and may produce false prediction if the samples in the support set happen to lie around the distribution boundary of different classes. To solve this issue, we present P3DC-Shot, an improved nearest-neighbor based few-shot classification method empowered by prior-driven data calibration. Inspired by the distribution calibration technique which utilizes the distribution or statistics of the base classes to calibrate the data for few-shot tasks, we propose a novel discrete data calibration operation which is more suitable for NN-based few-shot classification. Specifically, we treat the prototypes representing each base class as priors and calibrate each support data based on its similarity to different base prototypes. Then, we perform NN classification using these discretely calibrated support data. Results from extensive experiments on various datasets show our efficient non-learning based method can outperform or at least comparable to SOTA methods which need additional learning steps.

In this tutorial paper, we look into the evolution and prospect of network architecture and propose a novel conceptual architecture for the 6th generation (6G) networks. The proposed architecture has two key elements, i.e., holistic network virtualization and pervasive artificial intelligence (AI). The holistic network virtualization consists of network slicing and digital twin, from the aspects of service provision and service demand, respectively, to incorporate service-centric and user-centric networking. The pervasive network intelligence integrates AI into future networks from the perspectives of networking for AI and AI for networking, respectively. Building on holistic network virtualization and pervasive network intelligence, the proposed architecture can facilitate three types of interplay, i.e., the interplay between digital twin and network slicing paradigms, between model-driven and data-driven methods for network management, and between virtualization and AI, to maximize the flexibility, scalability, adaptivity, and intelligence for 6G networks. We also identify challenges and open issues related to the proposed architecture. By providing our vision, we aim to inspire further discussions and developments on the potential architecture of 6G.

In this paper, we investigate the joint device activity and data detection in massive machine-type communications (mMTC) with a one-phase non-coherent scheme, where data bits are embedded in the pilot sequences and the base station simultaneously detects active devices and their embedded data bits without explicit channel estimation. Due to the correlated sparsity pattern introduced by the non-coherent transmission scheme, the traditional approximate message passing (AMP) algorithm cannot achieve satisfactory performance. Therefore, we propose a deep learning (DL) modified AMP network (DL-mAMPnet) that enhances the detection performance by effectively exploiting the pilot activity correlation. The DL-mAMPnet is constructed by unfolding the AMP algorithm into a feedforward neural network, which combines the principled mathematical model of the AMP algorithm with the powerful learning capability, thereby benefiting from the advantages of both techniques. Trainable parameters are introduced in the DL-mAMPnet to approximate the correlated sparsity pattern and the large-scale fading coefficient. Moreover, a refinement module is designed to further advance the performance by utilizing the spatial feature caused by the correlated sparsity pattern. Simulation results demonstrate that the proposed DL-mAMPnet can significantly outperform traditional algorithms in terms of the symbol error rate performance.

The surrogate loss of variational autoencoders (VAEs) poses various challenges to their training, inducing the imbalance between task fitting and representation inference. To avert this, the existing strategies for VAEs focus on adjusting the tradeoff by introducing hyperparameters, deriving a tighter bound under some mild assumptions, or decomposing the loss components per certain neural settings. VAEs still suffer from uncertain tradeoff learning.We propose a novel evolutionary variational autoencoder (eVAE) building on the variational information bottleneck (VIB) theory and integrative evolutionary neural learning. eVAE integrates a variational genetic algorithm into VAE with variational evolutionary operators including variational mutation, crossover, and evolution. Its inner-outer-joint training mechanism synergistically and dynamically generates and updates the uncertain tradeoff learning in the evidence lower bound (ELBO) without additional constraints. Apart from learning a lossy compression and representation of data under the VIB assumption, eVAE presents an evolutionary paradigm to tune critical factors of VAEs and deep neural networks and addresses the premature convergence and random search problem by integrating evolutionary optimization into deep learning. Experiments show that eVAE addresses the KL-vanishing problem for text generation with low reconstruction loss, generates all disentangled factors with sharp images, and improves the image generation quality,respectively. eVAE achieves better reconstruction loss, disentanglement, and generation-inference balance than its competitors.